Dead cells timekeeper12/27/2023 ![]() With regards to life history theory it functions as the key variable mediating the correlation between life history traits. With regards to morphological evolution the oscillator, through alterations to developmental timing, controls change in size and shape. In advanced metazoans, where senescent cells are not continually replaced, it controls lifespan. It coordinates the timing of all cell-cell signalling systems, hence controls the timing of development and aging/senescence. In multicellular metazoans the oscillator remains synchronised across all cells. Cells such as neurons could be sustained throughout life, enabling the evolution of brains, hence, complex behaviour and intelligence. ![]() With increasing cell longevity, continual replacement of all senescent cells was no longer necessary. As the longevity of these cells was still relatively short in more primitive metazoans, stem cells, capable of differentiating into all specialised cell types, were retained in order to replace senescent cells. Slower oscillatory frequencies directed metazoan evolution towards extended longevity of individual cells, enabling generation of many specialised types of terminally differentiated cells. This was achieved through an intracellular oscillator, dubbed 'Life's Timekeeper', which evolved in the hypothetical ancestor of all metazoans. It is proposed that a primary and fundamental aspect of metazoan evolution is an ability to control and extend the longevity of individual cells.
0 Comments
Leave a Reply.AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |